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The boxed warning specifically contraindicates tirzepatide use in patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
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Some case reports have revealed that Pso symptoms can deteriorate soon after patients start GLP-1RA therapy, which indicates that these medications may activate immune dysregulation instead of providing suppression in certain individuals [20]
side effects experienced
What are the downsides
Real-world data on effectiveness and safety may differ from findings in controlled studies, highlighting the need for additional larger-scale studies and real-world data to guide clinical decision-making
